Human Leukocyte Antigen Gene Polymorphism and the Histocompatibility Laboratory
نویسندگان
چکیده
منابع مشابه
Analysis of Human Leukocyte Antigen class II Gene Polymorphism in Iranian Patients with Papillon-Lefevre Syndrome: a Family Study
Background: Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early development of aggressive pe-riodontitis. Although cathepsin C (CTSC) gene mutations have been established in about 70-80% of PLS patients, it is assumed that the patients may have dysfunctioning of immune defense mechanisms. Objective: To assess the associat...
متن کاملassociation of the maternal 14-bp insertion/deletion polymorphism in the histocompatibility leukocyte antigen g gene with recurrent implantation failure
background: implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of assisted reproductive techniques. hla-g, one of the non-classic hla subtypes, seems to have a vital role in neutralizing of mother immune system. according to importance of ins/del polymorphism of hla-g in regulation of hla-g expression, it seems that this polymorphism has a...
متن کاملP-164: Human Leukocyte Antigen Class Ib and Pregnancy Success
Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The Human Leucocyte Antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...
متن کاملAssociation of the maternal 14-bp insertion/deletion polymorphism in the histocompatibility leukocyte antigen G gene with recurrent implantation failure
BACKGROUND Implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of Assisted Reproductive Techniques. HLA-G, one of the non-classic HLA subtypes, seems to have a vital role in neutralizing of mother immune system. According to importance of ins/del polymorphism of HLA-G in regulation of HLA-G expression, it seems that this polymorphism has an...
متن کاملP-145: Role of Human Leukocyte Antigen in Miscarriage
Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The human leucocyte antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Molecular Diagnostics
سال: 2001
ISSN: 1525-1578
DOI: 10.1016/s1525-1578(10)60658-7